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The promise of discovering population-specific disease-associated genes in South Asia.

Nakatsuka N, Moorjani P, Rai N, et al. The promise of discovering population-specific disease-associated genes in South Asia. Nat Genet. 2017;49(9):1403-1407. doi:10.1038/ng.3917

Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections.

Early AM, Lievens M, MacInnis BL, et al. Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections. Nat Commun. 2018;9(1):1381. doi:10.1038/s41467-018-03807-7

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

Patsopoulos NA, Bayer Pharma MS Genetics Working Group, Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist, et al. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol. 2011;70(6):897-912. doi:10.1002/ana.22609

Searching for missing heritability: designing rare variant association studies.

Zuk O, Schaffner SF, Samocha K, et al. Searching for missing heritability: designing rare variant association studies. Proc Natl Acad Sci U S A. 2014;111(4):E455-64. doi:10.1073/pnas.1322563111

Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations.

Okada Y, Kim K, Han B, et al. Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations. Hum Mol Genet. 2014;23(25):6916-26. doi:10.1093/hmg/ddu387

APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL.

Gesierich B, Opherk C, Rosand J, et al. APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL. J Cereb Blood Flow Metab. 2016;36(1):199-203. doi:10.1038/jcbfm.2015.85

Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation.

Croteau-Chonka DC, Rogers AJ, Raj T, et al. Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation. PLoS One. 2015;10(10):e0140758. doi:10.1371/journal.pone.0140758

Genetics of human cardiovascular disease.

Kathiresan S, Srivastava D. Genetics of human cardiovascular disease. Cell. 2012;148(6):1242-57. doi:10.1016/j.cell.2012.03.001

Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data.

Radmanesh F, Devan WJ, Anderson CD, Rosand J, Falcone GJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI). Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data. Eur J Hum Genet. 2014;22(10):1239-42. doi:10.1038/ejhg.2013.308

Distribution and medical impact of loss-of-function variants in the Finnish founder population.

Lim ET, Würtz P, Havulinna AS, et al. Distribution and medical impact of loss-of-function variants in the Finnish founder population. PLoS Genet. 2014;10(7):e1004494. doi:10.1371/journal.pgen.1004494