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CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms.

Shapiro RS, Chavez A, Collins JJ. CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms. Nat Rev Microbiol. 2018;16(6):333-339. doi:10.1038/s41579-018-0002-7

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines.

Ellrott K, Bailey MH, Saksena G, et al. Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Syst. 2018;6(3):271-281.e7. doi:10.1016/j.cels.2018.03.002

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.

Schaub FX, Dhankani V, Berger AC, et al. Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Syst. 2018;6(3):282-300.e2. doi:10.1016/j.cels.2018.03.003

Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases.

Chen F, Zhang Y, Gibbons DL, et al. Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases. Clin Cancer Res. 2018;24(9):2182-2193. doi:10.1158/1078-0432.CCR-17-3378

Reconstructing the genetic history of late Neanderthals.

Hajdinjak M, Fu Q, Hübner A, et al. Reconstructing the genetic history of late Neanderthals. Nature. 2018;555(7698):652-656. doi:10.1038/nature26151

Precise Cas9 targeting enables genomic mutation prevention.

Chavez A, Pruitt BW, Tuttle M, et al. Precise Cas9 targeting enables genomic mutation prevention. Proc Natl Acad Sci U S A. 2018;115(14):3669-3673. doi:10.1073/pnas.1718148115

Executive Function and Genomic Risk for Attention-Deficit/Hyperactivity Disorder: Testing Intermediate Phenotypes in the Context of Polygenic Risk.

Carey CE, Bogdan R. Executive Function and Genomic Risk for Attention-Deficit/Hyperactivity Disorder: Testing Intermediate Phenotypes in the Context of Polygenic Risk. J Am Acad Child Adolesc Psychiatry. 2018;57(3):146-148. doi:10.1016/j.jaac.2018.01.003

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

Baillie K, Bretherick A, Haley CS, et al. Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease. PLoS Comput Biol. 2018;14(3):e1005934. doi:10.1371/journal.pcbi.1005934

A comprehensive genomic history of extinct and living elephants.

Palkopoulou E, Lipson M, Mallick S, et al. A comprehensive genomic history of extinct and living elephants. Proc Natl Acad Sci U S A. 2018;115(11):E2566-E2574. doi:10.1073/pnas.1720554115

Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma.

Pectasides E, Stachler MD, Derks S, et al. Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma. Cancer Discov. 2018;8(1):37-48. doi:10.1158/2159-8290.CD-17-0395