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Electrophilic activity-based RNA probes reveal a self-alkylating RNA for RNA labeling.

McDonald RI, Guilinger JP, Mukherji S, Curtis EA, Lee WI, Liu DR. Electrophilic activity-based RNA probes reveal a self-alkylating RNA for RNA labeling. Nat Chem Biol. 2014;10(12):1049-54. doi:10.1038/nchembio.1655

Small molecule-triggered Cas9 protein with improved genome-editing specificity.

Davis KM, Pattanayak V, Thompson DB, Zuris JA, Liu DR. Small molecule-triggered Cas9 protein with improved genome-editing specificity. Nat Chem Biol. 2015;11(5):316-8. doi:10.1038/nchembio.1793

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.

Hubbard BP, Badran AH, Zuris JA, et al. Continuous directed evolution of DNA-binding proteins to improve TALEN specificity. Nat Methods. 2015;12(10):939-42. doi:10.1038/nmeth.3515

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature. 2016;533(7603):420-4. doi:10.1038/nature17946

Scientific commentary: the scientific foundations and medical and social prospects of the Human Genome Project.

Lander ES. Scientific commentary: the scientific foundations and medical and social prospects of the Human Genome Project. J Law Med Ethics. 1998;26(3):184-8, 178.

Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome.

Wang DG, Fan JB, Siao CJ, et al. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science. 1998;280(5366):1077-82.

Effects of medical research on health care and economy.

Pardes H, Manton KG, Lander ES, Tolley HD, Ullian AD, Palmer H. Effects of medical research on health care and economy. Science. 1999;283(5398):36-7.

A physical map of 30,000 human genes.

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The plasticity of dendritic cell responses to pathogens and their components.

Huang Q, Liu D, Majewski P, et al. The plasticity of dendritic cell responses to pathogens and their components. Science. 2001;294(5543):870-5. doi:10.1126/science.294.5543.870

A magnetic attraction to high-throughput genomics.

Hawkins TL, McKernan KJ, Jacotot LB, MacKenzie JB, Richardson PM, Lander ES. A magnetic attraction to high-throughput genomics. Science. 1997;276(5320):1887-9.