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Cell lineage analysis in human brain using endogenous retroelements.

Evrony GD, Lee E, Mehta BK, et al. Cell lineage analysis in human brain using endogenous retroelements. Neuron. 2015;85(1):49-59. doi:10.1016/j.neuron.2014.12.028

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.

Wang S, Tsun ZY, Wolfson RL, et al. Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. Science. 2015;347(6218):188-94. doi:10.1126/science.1257132

Gene expression analysis identifies global gene dosage sensitivity in cancer.

Fehrmann RSN, Karjalainen JM, Krajewska M, et al. Gene expression analysis identifies global gene dosage sensitivity in cancer. Nat Genet. 2015;47(2):115-25. doi:10.1038/ng.3173

No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans.

Do R, Balick D, Li H, Adzhubei I, Sunyaev S, Reich D. No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans. Nat Genet. 2015;47(2):126-31. doi:10.1038/ng.3186

Using cross-classified multilevel models to disentangle school and neighborhood effects: an example focusing on smoking behaviors among adolescents in the United States.

Dunn EC, Richmond TK, Milliren CE, Subramanian SV. Using cross-classified multilevel models to disentangle school and neighborhood effects: an example focusing on smoking behaviors among adolescents in the United States. Health Place. 2015;31:224-32. doi:10.1016/j.healthplace.2014.12.001

Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions.

Xu J, Shao Z, Li D, et al. Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions. Mol Cell. 2015;57(2):304-16. doi:10.1016/j.molcel.2014.12.009

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts.

Würtz P, Havulinna AS, Soininen P, et al. Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts. Circulation. 2015;131(9):774-85. doi:10.1161/CIRCULATIONAHA.114.013116

A mechanism for asymmetric cell division resulting in proliferative asynchronicity.

Dey-Guha I, Alves CP, Yeh AC, Sole X, Darp R, Ramaswamy S. A mechanism for asymmetric cell division resulting in proliferative asynchronicity. Mol Cancer Res. 2015;13(2):223-30. doi:10.1158/1541-7786.MCR-14-0474

Pluripotency transcription factor Oct4 mediates stepwise nucleosome demethylation and depletion.

Shakya A, Callister C, Goren A, et al. Pluripotency transcription factor Oct4 mediates stepwise nucleosome demethylation and depletion. Mol Cell Biol. 2015;35(6):1014-25. doi:10.1128/MCB.01105-14

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.

Roberts AM, Ware JS, Herman DS, et al. Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med. 2015;7(270):270ra6. doi:10.1126/scitranslmed.3010134