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Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.

Giani FC, Fiorini C, Wakabayashi A, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. 2016;18(1):73-8. doi:10.1016/j.stem.2015.09.015

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.

Felix JF, Bradfield JP, Monnereau C, et al. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet. 2016;25(2):389-403. doi:10.1093/hmg/ddv472

Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk.

Rand KA, Rohland N, Tandon A, et al. Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk. Hum Mol Genet. 2016;25(2):371-81. doi:10.1093/hmg/ddv462

EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects.

Peng Q, Li J, Tan J, et al. EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects. Hum Genet. 2016;135(1):99-108. doi:10.1007/s00439-015-1618-6

Reduced Sleep Spindles in Schizophrenia: A Treatable Endophenotype That Links Risk Genes to Impaired Cognition?

Manoach DS, Pan JQ, Purcell SM, Stickgold R. Reduced Sleep Spindles in Schizophrenia: A Treatable Endophenotype That Links Risk Genes to Impaired Cognition? Biol Psychiatry. 2016;80(8):599-608. doi:10.1016/j.biopsych.2015.10.003

Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy.

Dejanovic B, Djémié T, Grünewald N, et al. Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy. EMBO Mol Med. 2015;7(12):1580-94. doi:10.15252/emmm.201505323

Advances in discovering small molecules to probe protein function in a systems context.

Doyle SK, Pop MS, Evans HL, Koehler AN. Advances in discovering small molecules to probe protein function in a systems context. Curr Opin Chem Biol. 2016;30:28-36. doi:10.1016/j.cbpa.2015.10.032

Prediction of sudden cardiac death with automated high-throughput analysis of heterogeneity in standard resting 12-lead electrocardiograms.

Kenttä TV, Nearing BD, Porthan K, et al. Prediction of sudden cardiac death with automated high-throughput analysis of heterogeneity in standard resting 12-lead electrocardiograms. Heart Rhythm. 2016;13(3):713-20. doi:10.1016/j.hrthm.2015.11.035

Large Scale Genetic Research on Neuropsychiatric Disorders in African Populations is Needed.

Dalvie S, Koen N, Duncan L, et al. Large Scale Genetic Research on Neuropsychiatric Disorders in African Populations is Needed. EBioMedicine. 2015;2(10):1259-61. doi:10.1016/j.ebiom.2015.10.002

Rationally engineered Cas9 nucleases with improved specificity.

Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Rationally engineered Cas9 nucleases with improved specificity. Science. 2016;351(6268):84-8. doi:10.1126/science.aad5227