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Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis.

Hoshida Y, Villanueva A, Sangiovanni A, et al. Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis. Gastroenterology. 2013;144(5):1024-30. doi:10.1053/j.gastro.2013.01.021

MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.

Plovanich M, Bogorad RL, Sancak Y, et al. MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling. PLoS One. 2013;8(2):e55785. doi:10.1371/journal.pone.0055785

A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax.

March S, Ng S, Velmurugan S, et al. A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host Microbe. 2013;14(1):104-15. doi:10.1016/j.chom.2013.06.005

A Central role for mTOR in lipid homeostasis.

Lamming DW, Sabatini DM. A Central role for mTOR in lipid homeostasis. Cell Metab. 2013;18(4):465-9. doi:10.1016/j.cmet.2013.08.002

Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia.

Stitziel NO, Fouchier SW, Sjouke B, et al. Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia. Arterioscler Thromb Vasc Biol. 2013;33(12):2909-14. doi:10.1161/ATVBAHA.113.302426

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.

Consortium STD 2, Williams AL, Jacobs SBR, et al. Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature. 2014;506(7486):97-101. doi:10.1038/nature12828

S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury.

Cox AG, Saunders DC, Kelsey PB, et al. S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury. Cell Rep. 2014;6(1):56-69. doi:10.1016/j.celrep.2013.12.007

β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.

Roberts LD, Boström P, O’Sullivan JF, et al. β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014;19(1):96-108. doi:10.1016/j.cmet.2013.12.003

Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth.

Nissim S, Sherwood RI, Wucherpfennig J, et al. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014;28(4):423-37. doi:10.1016/j.devcel.2014.01.006

RagA, but not RagB, is essential for embryonic development and adult mice.

Efeyan A, Schweitzer LD, Bilate AM, et al. RagA, but not RagB, is essential for embryonic development and adult mice. Dev Cell. 2014;29(3):321-9. doi:10.1016/j.devcel.2014.03.017