ӳ��ý

In vivo genome editing using Staphylococcus aureus Cas9.

Ran A, Cong L, Yan WX, et al. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 2015;520(7546):186-91. doi:10.1038/nature14299

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.

Agerbo E, Sullivan PF, Vilhjálmsson BJ, et al. Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis. JAMA Psychiatry. 2015;72(7):635-41. doi:10.1001/jamapsychiatry.2015.0346

Association of a brain methylation site with clinical outcomes in depression does not replicate across populations.

Uher R, Ripke S, Müller-Myhsok B, Lewis CM, Perlis RH. Association of a brain methylation site with clinical outcomes in depression does not replicate across populations. Am J Psychiatry. 2015;172(4):395-7. doi:10.1176/appi.ajp.2015.14101348

Frozen encapsulated stool in recurrent Clostridium difficile: exploring the role of pills in the treatment hierarchy of fecal microbiota transplant nonresponders.

Stollman N, Smith M, Giovanelli A, et al. Frozen encapsulated stool in recurrent Clostridium difficile: exploring the role of pills in the treatment hierarchy of fecal microbiota transplant nonresponders. Am J Gastroenterol. 2015;110(4):600-1. doi:10.1038/ajg.2015.81

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis.

Miao J, Ling AV, Manthena PV, et al. Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis. Nat Commun. 2015;6:6498. doi:10.1038/ncomms7498

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction.

Akizu N, Cantagrel V, Zaki MS, et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;47(5):528-34. doi:10.1038/ng.3256

Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats.

Lundh M, Galbo T, Poulsen SS, Mandrup-Poulsen T. Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats. Diabetes Obes Metab. 2015;17(7):703-7. doi:10.1111/dom.12470

Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development.

Chan Y, Salem RM, Hsu YHH, et al. Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development. Am J Hum Genet. 2015;96(5):695-708. doi:10.1016/j.ajhg.2015.02.018

Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination.

Nakayama T, Al-Maawali A, El-Quessny M, et al. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum Genet. 2015;96(5):709-19. doi:10.1016/j.ajhg.2015.03.003

Distinct metabolomic signatures are associated with longevity in humans.

Cheng S, Larson MG, McCabe EL, et al. Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015;6:6791. doi:10.1038/ncomms7791