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Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.

Malik R, Bevan S, Nalls MA, et al. Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. Stroke. 2014;45(2):394-402. doi:10.1161/STROKEAHA.113.002938

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.

Peloso GM, Auer PL, Bis JC, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014;94(2):223-32. doi:10.1016/j.ajhg.2014.01.009

Common genetic variants modulate pathogen-sensing responses in human dendritic cells.

Lee MN, Ye C, Villani AC, et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science. 2014;343(6175):1246980. doi:10.1126/science.1246980

Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis.

Rampal R, Al-Shahrour F, Abdel-Wahab O, et al. Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis. Blood. 2014;123(22):e123-33. doi:10.1182/blood-2014-02-554634

Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.

Pugh TJ, Yu W, Yang J, et al. Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences. Oncogene. 2014;33(45):5295-302. doi:10.1038/onc.2014.150

Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.

Du M, Auer PL, Jiao S, et al. Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans. Hum Mol Genet. 2014;23(24):6607-15. doi:10.1093/hmg/ddu361

Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation.

Bejar R, Stevenson KE, Caughey B, et al. Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation. J Clin Oncol. 2014;32(25):2691-8. doi:10.1200/JCO.2013.52.3381

Effect of phosphodiesterase inhibition on insulin resistance in obese individuals.

Ho JE, Arora P, Walford GA, et al. Effect of phosphodiesterase inhibition on insulin resistance in obese individuals. J Am Heart Assoc. 2014;3(5):e001001. doi:10.1161/JAHA.114.001001

Does poor health predict moving, move quality, and desire to move?: A study examining neighborhood selection in US adolescents and adults.

Dunn EC, Winning A, Zaika N, Subramanian SV. Does poor health predict moving, move quality, and desire to move?: A study examining neighborhood selection in US adolescents and adults. Health Place. 2014;30:154-64. doi:10.1016/j.healthplace.2014.08.007

Leveraging population admixture to characterize the heritability of complex traits.

Zaitlen N, Pasaniuc B, Sankararaman S, et al. Leveraging population admixture to characterize the heritability of complex traits. Nat Genet. 2014;46(12):1356-62. doi:10.1038/ng.3139