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Leukemia-specific delivery of mutant NOTCH1 targeted therapy.

Roti G, Qi J, Kitara S, et al. Leukemia-specific delivery of mutant NOTCH1 targeted therapy. J Exp Med. 2018;215(1):197-216. doi:10.1084/jem.20151778

Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias.

D’Gama AM, Woodworth MB, Hossain AA, et al. Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias. Cell Rep. 2017;21(13):3754-3766. doi:10.1016/j.celrep.2017.11.106

Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development.

Lupberger J, Croonenborghs T, Suarez AAR, et al. Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development. Gastroenterology. 2019;157(2):537-551.e9. doi:10.1053/j.gastro.2019.04.003

Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.

Wang G, Chow RD, Ye L, et al. Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Sci Adv. 2018;4(2):eaao5508. doi:10.1126/sciadv.aao5508

Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations.

Fulco CP, Nasser J, Jones TR, et al. Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations. Nat Genet. 2019;51(12):1664-1669. doi:10.1038/s41588-019-0538-0

Disparate levels of beta-catenin activity determine nephron progenitor cell fate.

Ramalingam H, Fessler AR, Das A, et al. Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018;440(1):13-21. doi:10.1016/j.ydbio.2018.04.020

Perspectives on ENCODE.

ENCODE Project Consortium, Snyder MP, Gingeras TR, et al. Perspectives on ENCODE. Nature. 2020;583(7818):693-698. doi:10.1038/s41586-020-2449-8

Regulation of DNA repair in the absence of classical non-homologous end joining.

Kang YJ, Yan CT. Regulation of DNA repair in the absence of classical non-homologous end joining. DNA Repair (Amst). 2018;68:34-40. doi:10.1016/j.dnarep.2018.06.001

The identification of myriocin-binding proteins.

Chen JK, Lane WS, Schreiber SL. The identification of myriocin-binding proteins. Chem Biol. 1999;6(4):221-35. doi:10.1016/S1074-5521(99)80038-6

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin.

Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, Schreiber SL. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science. 1995;268(5211):726-31.