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The human gut microbiome in early-onset type 1 diabetes from the TEDDY study.

Vatanen T, Franzosa EA, Schwager R, et al. The human gut microbiome in early-onset type 1 diabetes from the TEDDY study. Nature. 2018;562(7728):589-594. doi:10.1038/s41586-018-0620-2

Targeting nuclear receptor NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity.

Zhang Y, Federation AJ, Kim S, et al. Targeting nuclear receptor NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity. J Clin Invest. 2018;128(11):4898-4911. doi:10.1172/JCI98353

is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing.

Beauchamp EM, Leventhal M, Bernard E, et al. is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021;2(5):500-517. doi:10.1158/2643-3230.BCD-20-0224

Gene Expression of Diverse Cryptococcus Isolates during Infection of the Human Central Nervous System.

Yu CH, Sephton-Clark P, Tenor JL, et al. Gene Expression of Diverse Cryptococcus Isolates during Infection of the Human Central Nervous System. mBio. 2021;12(6):e0231321. doi:10.1128/mBio.02313-21

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris.

Iyer KR, Camara K, Daniel-Ivad M, et al. An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris. Nat Commun. 2020;11(1):6429. doi:10.1038/s41467-020-20183-3

Burden Testing of Rare Variants Identified through Exome Sequencing via Publicly Available Control Data.

Guo MH, Plummer L, Chan YM, Hirschhorn JN, Lippincott MF. Burden Testing of Rare Variants Identified through Exome Sequencing via Publicly Available Control Data. Am J Hum Genet. 2018;103(4):522-534. doi:10.1016/j.ajhg.2018.08.016

Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study.

Shen J, Xiao R, Bair J, et al. Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study. Cell Death Dis. 2018;9(10):1018. doi:10.1038/s41419-018-1049-0

Identification of Antinorovirus Genes in Human Cells Using Genome-Wide CRISPR Activation Screening.

Orchard RC, Sullender ME, Dunlap BF, Balce DR, Doench JG, Virgin HW. Identification of Antinorovirus Genes in Human Cells Using Genome-Wide CRISPR Activation Screening. J Virol. 2019;93(1). doi:10.1128/JVI.01324-18

Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin.

Wang JS, Kamath T, Mazur CM, et al. Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin. Nat Commun. 2021;12(1):6271. doi:10.1038/s41467-021-26571-7

Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes.

Tiwari N, Pataskar A, Péron S, et al. Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes. Cell Stem Cell. 2018;23(4):557-571.e8. doi:10.1016/j.stem.2018.09.008