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Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer.

Forsberg LA, Rasi C, Malmqvist N, et al. Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. Nat Genet. 2014;46(6):624-8. doi:10.1038/ng.2966

Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort.

Saxena R, Bjonnes A, Prescott J, et al. Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort. Circ Cardiovasc Genet. 2014;7(3):287-95. doi:10.1161/CIRCGENETICS.113.000412

Biallelic variants in TTLL5, encoding a tubulin glutamylase, cause retinal dystrophy.

Sergouniotis PI, Chakarova C, Murphy C, et al. Biallelic variants in TTLL5, encoding a tubulin glutamylase, cause retinal dystrophy. Am J Hum Genet. 2014;94(5):760-9. doi:10.1016/j.ajhg.2014.04.003

Life extension factor klotho enhances cognition.

Dubal DB, Yokoyama JS, Zhu L, et al. Life extension factor klotho enhances cognition. Cell Rep. 2014;7(4):1065-76. doi:10.1016/j.celrep.2014.03.076

Selectivity in genetic association with sub-classified migraine in women.

Chasman DI, Anttila V, Buring JE, et al. Selectivity in genetic association with sub-classified migraine in women. PLoS Genet. 2014;10(5):e1004366. doi:10.1371/journal.pgen.1004366

A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups.

Weng LC, Tang W, Rich SS, et al. A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups. Thromb Res. 2014;134(2):462-7. doi:10.1016/j.thromres.2014.05.018

Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.

Consortium STD 2, Estrada K, Aukrust I, et al. Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population. JAMA. 2014;311(22):2305-14. doi:10.1001/jama.2014.6511

Improving accuracy of rare variant imputation with a two-step imputation approach.

Kreiner-Møller E, Medina-Gomez C, Uitterlinden AG, Rivadeneira F, Estrada K. Improving accuracy of rare variant imputation with a two-step imputation approach. Eur J Hum Genet. 2015;23(3):395-400. doi:10.1038/ejhg.2014.91

Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes.

Walford GA, Porneala BC, Dauriz M, et al. Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes. Diabetes Care. 2014;37(9):2508-14. doi:10.2337/dc14-0560

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Arking DE, Pulit SL, Crotti L, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet. 2014;46(8):826-36. doi:10.1038/ng.3014