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Cryo-electron microscopy structure of the lipid droplet-formation protein seipin.

Sui X, Arlt H, Brock KP, et al. Cryo-electron microscopy structure of the lipid droplet-formation protein seipin. J Cell Biol. 2018;217(12):4080-4091. doi:10.1083/jcb.201809067

Phosphocode-dependent functional dichotomy of a common co-receptor in plant signalling.

Perraki A, DeFalco TA, Derbyshire P, et al. Phosphocode-dependent functional dichotomy of a common co-receptor in plant signalling. Nature. 2018;561(7722):248-252. doi:10.1038/s41586-018-0471-x

An n→π* interaction reduces the electrophilicity of the acceptor carbonyl group.

Choudhary A, Fry CG, Kamer KJ, Raines RT. An n→π* interaction reduces the electrophilicity of the acceptor carbonyl group. Chem Commun (Camb). 2013;49(74):8166-8. doi:10.1039/c3cc44573a

Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements.

Ferrer M, Kapoor TM, Strassmaier T, et al. Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nat Struct Biol. 1999;6(10):953-60. doi:10.1038/13324

Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules.

Bowman MR, MacFerrin KD, Schreiber SL, Burakoff SJ. Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules. Proc Natl Acad Sci U S A. 1990;87(22):9052-6.

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

Jin YJ, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ. Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. Proc Natl Acad Sci U S A. 1991;88(15):6677-81.

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin.

Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J. Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. J Mol Biol. 1993;229(1):105-24. doi:10.1006/jmbi.1993.1012

Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743.

Martinez EJ, Owa T, Schreiber SL, Corey EJ. Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743. Proc Natl Acad Sci U S A. 1999;96(7):3496-501.

Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway.

Chan P, Han X, Zheng B, et al. Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway. Nat Chem Biol. 2016;12(4):282-9. doi:10.1038/nchembio.2036

Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A.

Ke H, Mayrose D, Belshaw PJ, et al. Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A. Structure. 1994;2(1):33-44.