Lim ET, Liu YP, Chan Y, et al. A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity. Am J Hum Genet. 2014;95(5):509-20. doi:10.1016/j.ajhg.2014.09.015
Pringle PL, Stewart KO, Peloquin JM, et al. Body Mass Index, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn’s Disease. Inflamm Bowel Dis. 2015;21(10):2304-10. doi:10.1097/MIB.0000000000000498
Maianti JP, McFedries A, Foda ZH, et al. Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature. 2014;511(7507):94-8. doi:10.1038/nature13297
Singer JB, Hill AE, Burrage LC, et al. Genetic dissection of complex traits with chromosome substitution strains of mice. Science. 2004;304(5669):445-8. doi:10.1126/science.1093139
Kang S, Tsai LT, Zhou Y, et al. Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Nat Cell Biol. 2015;17(1):44-56. doi:10.1038/ncb3080
Yang L, Calay ES, Fan J, et al. METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction. Science. 2015;349(6247):500-6. doi:10.1126/science.aaa0079
Reshef DN, Reshef YA, Finucane HK, et al. Detecting novel associations in large data sets. Science. 2011;334(6062):1518-24. doi:10.1126/science.1205438
Locke AE, Kahali B, Berndt SI, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206. doi:10.1038/nature14177
Papandonatos GD, Pan Q, Pajewski NM, et al. Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials. Diabetes. 2015;64(12):4312-21. doi:10.2337/db15-0441
Düvel K, Yecies JL, Menon S, et al. Activation of a metabolic gene regulatory network downstream of mTOR complex 1. Mol Cell. 2010;39(2):171-83. doi:10.1016/j.molcel.2010.06.022