Sidow A, Bulotsky MS, Kerrebrock AW, et al. Serrate2 is disrupted in the mouse limb-development mutant syndactylism. Nature. 1997;389(6652):722-5. doi:10.1038/39587
Wade CM, Kulbokas EJ, Kirby AW, et al. The mosaic structure of variation in the laboratory mouse genome. Nature. 2002;420(6915):574-8. doi:10.1038/nature01252
Nadeau JH, Singer JB, Matin A, Lander ES. Analysing complex genetic traits with chromosome substitution strains. Nat Genet. 2000;24(3):221-5. doi:10.1038/73427
Altshuler D, Hirschhorn JN, Klannemark M, et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet. 2000;26(1):76-80. doi:10.1038/79216
Cowles CR, Hirschhorn JN, Altshuler D, Lander ES. Detection of regulatory variation in mouse genes. Nat Genet. 2002;32(3):432-7. doi:10.1038/ng992
Lander ES, Botstein D. Strategies for studying heterogeneous genetic traits in humans by using a linkage map of restriction fragment length polymorphisms. Proc Natl Acad Sci U S A. 1986;83(19):7353-7.
Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466(7307):707-13. doi:10.1038/nature09270
Castro VM, Minnier J, Murphy SN, et al. Validation of electronic health record phenotyping of bipolar disorder cases and controls. Am J Psychiatry. 2015;172(4):363-72. doi:10.1176/appi.ajp.2014.14030423
Wagner BK, Clemons PA. Connecting synthetic chemistry decisions to cell and genome biology using small-molecule phenotypic profiling. Curr Opin Chem Biol. 2009;13(5-6):539-48. doi:10.1016/j.cbpa.2009.09.018
Johannessen CM, Clemons PA, Wagner BK. Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery. Trends Genet. 2015;31(1):16-23. doi:10.1016/j.tig.2014.11.002