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Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.

Shen K, Sabatini DM. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms. Proc Natl Acad Sci U S A. 2018;115(38):9545-9550. doi:10.1073/pnas.1811727115

Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns.

Javasky E, Shamir I, Gandhi S, et al. Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns. Genome Res. 2018;28(10):1455-1466. doi:10.1101/gr.230300.117

Signaling network model of chromatin.

Schreiber SL, Bernstein BE. Signaling network model of chromatin. Cell. 2002;111(6):771-8.

Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.

Mekhdjian AH, Kai F, Rubashkin MG, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017;28(11):1467-1488. doi:10.1091/mbc.E16-09-0654

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.

Seo J, Kritskiy O, Watson A, et al. Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia. J Neurosci. 2017;37(41):9917-9924. doi:10.1523/JNEUROSCI.0621-17.2017

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint.

Nghiem P, Park PK, Ys Y son K, Desai BN, Schreiber SL. ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint. J Biol Chem. 2002;277(6):4428-34. doi:10.1074/jbc.M106113200

An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling.

Mertins P, Przybylski D, Yosef N, et al. An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling. Cell Rep. 2017;19(13):2853-2866. doi:10.1016/j.celrep.2017.06.016

Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways.

Stump B, Shrestha S, Lamattina AM, et al. Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways. PLoS One. 2019;14(4):e0213831. doi:10.1371/journal.pone.0213831

Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation.

Pflum MK, Tong JK, Lane WS, Schreiber SL. Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation. J Biol Chem. 2001;276(50):47733-41. doi:10.1074/jbc.M105590200

Predator odor evokes sex-independent stress responses in male and female Wistar rats and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein in the male, but not the female hippocampus.

Homiack D, O’Cinneide E, Hajmurad S, et al. Predator odor evokes sex-independent stress responses in male and female Wistar rats and reduces phosphorylation of cyclic-adenosine monophosphate response element binding protein in the male, but not the female hippocampus. Hippocampus. 2017;27(9):1016-1029. doi:10.1002/hipo.22749