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RBSURFpred: Modeling protein accessible surface area in real and binary space using regularized and optimized regression.

Tarafder S, Ahmed MT, Iqbal S, Hoque MT, Rahman S. RBSURFpred: Modeling protein accessible surface area in real and binary space using regularized and optimized regression. J Theor Biol. 2018;441:44-57. doi:10.1016/j.jtbi.2017.12.029

Identification of pathogenic variant enriched regions across genes and gene families.

Pérez-Palma E, May P, Iqbal S, et al. Identification of pathogenic variant enriched regions across genes and gene families. Genome Res. 2020;30(1):62-71. doi:10.1101/gr.252601.119

Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn.

Mezo AR, McDonnell KA, Hehir CAT, et al. Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn. Proc Natl Acad Sci U S A. 2008;105(7):2337-42. doi:10.1073/pnas.0708960105

Critical assessment of protein intrinsic disorder prediction.

Necci M, Piovesan D, CAID Predictors, DisProt Curators, Tosatto SCE. Critical assessment of protein intrinsic disorder prediction. Nat Methods. 2021;18(5):472-481. doi:10.1038/s41592-021-01117-3

Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs.

Weingarten-Gabbay S, Klaeger S, Sarkizova S, et al. Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs. Cell. 2021;184(15):3962-3980.e17. doi:10.1016/j.cell.2021.05.046

Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants.

Iqbal S, Pérez-Palma E, Jespersen JB, et al. Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants. Proc Natl Acad Sci U S A. 2020;117(45):28201-28211. doi:10.1073/pnas.2002660117

Recessive MYF5 Mutations Cause External Ophthalmoplegia, Rib, and Vertebral Anomalies.

Di Gioia SA, Shaaban S, Tuysuz B, et al. Recessive MYF5 Mutations Cause External Ophthalmoplegia, Rib, and Vertebral Anomalies. Am J Hum Genet. 2018;103(1):115-124. doi:10.1016/j.ajhg.2018.05.003

Structure-activity relationships of a peptide inhibitor of the human FcRn:human IgG interaction.

Mezo AR, McDonnell KA, Castro A, Fraley C. Structure-activity relationships of a peptide inhibitor of the human FcRn:human IgG interaction. Bioorg Med Chem. 2008;16(12):6394-405. doi:10.1016/j.bmc.2008.05.004

In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design.

Porto WF, Irazazabal L, Alves ESF, et al. In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nat Commun. 2018;9(1):1490. doi:10.1038/s41467-018-03746-3

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3.

Herrera KNG, Zaganjor E, Ishikawa Y, et al. Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3. Cell Rep. 2018;22(8):1945-1955. doi:10.1016/j.celrep.2018.01.076