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Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.

Shen K, Sabatini DM. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms. Proc Natl Acad Sci U S A. 2018;115(38):9545-9550. doi:10.1073/pnas.1811727115

Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression.

Fiziev P, Akdemir KC, Miller JP, et al. Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression. Cell Rep. 2017;19(4):875-889. doi:10.1016/j.celrep.2017.03.078

mTOR Signaling in Growth, Metabolism, and Disease.

Saxton RA, Sabatini DM. mTOR Signaling in Growth, Metabolism, and Disease. Cell. 2017;168(6):960-976. doi:10.1016/j.cell.2017.02.004

Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation.

Kim AR, Ulirsch JC, Wilmes S, et al. Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Cell. 2017;168(6):1053-1064.e15. doi:10.1016/j.cell.2017.02.026

The mutational landscape of head and neck squamous cell carcinoma.

Stransky N, Egloff AM, Tward AD, et al. The mutational landscape of head and neck squamous cell carcinoma. Science. 2011;333(6046):1157-60. doi:10.1126/science.1208130

Integrated genomic and molecular characterization of cervical cancer.

Cancer Genome Atlas Research Network, Albert Einstein College of Medicine, Analytical Biological Services, et al. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543(7645):378-384. doi:10.1038/nature21386

Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.

Mekhdjian AH, Kai F, Rubashkin MG, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017;28(11):1467-1488. doi:10.1091/mbc.E16-09-0654

Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python.

Andrew AL, Perry BW, Card DC, et al. Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python. BMC Genomics. 2017;18(1):338. doi:10.1186/s12864-017-3743-1

AKT kinase activity is required for lithium to modulate mood-related behaviors in mice.

Pan JQ, Lewis MC, Ketterman JK, et al. AKT kinase activity is required for lithium to modulate mood-related behaviors in mice. Neuropsychopharmacology. 2011;36(7):1397-411. doi:10.1038/npp.2011.24

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location.

Bram RJ, Hung DT, Martin PK, Schreiber SL, Crabtree GR. Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location. Mol Cell Biol. 1993;13(8):4760-9.