Mandal PK, Ferreira LMR, Collins R, et al. Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. Cell Stem Cell. 2014;15(5):643-52. doi:10.1016/j.stem.2014.10.004
Hu WF, Pomp O, Ben-Omran T, et al. Katanin p80 regulates human cortical development by limiting centriole and cilia number. Neuron. 2014;84(6):1240-57. doi:10.1016/j.neuron.2014.12.017
Ulirsch JC, Lacy JN, An X, Mohandas N, Mikkelsen TS, Sankaran VG. Altered chromatin occupancy of master regulators underlies evolutionary divergence in the transcriptional landscape of erythroid differentiation. PLoS Genet. 2014;10(12):e1004890. doi:10.1371/journal.pgen.1004890
Pasque V, Tchieu J, Karnik R, et al. X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell. 2014;159(7):1681-97. doi:10.1016/j.cell.2014.11.040
Haesemeyer M, Schier AF. The study of psychiatric disease genes and drugs in zebrafish. Curr Opin Neurobiol. 2015;30:122-30. doi:10.1016/j.conb.2014.12.002
Shema R, Kulicke R, Cowley GS, Stein R, Root DE, Heiman M. Synthetic lethal screening in the mammalian central nervous system identifies Gpx6 as a modulator of Huntington’s disease. Proc Natl Acad Sci U S A. 2015;112(1):268-72. doi:10.1073/pnas.1417231112
Baratta MG, Schinzel AC, Zwang Y, et al. An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma. Proc Natl Acad Sci U S A. 2015;112(1):232-7. doi:10.1073/pnas.1422165112
Martz CA, Ottina KA, Singleton KR, et al. Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014;7(357):ra121. doi:10.1126/scisignal.aaa1877
Godec J, Cowley GS, Barnitz A, et al. Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation. Proc Natl Acad Sci U S A. 2015;112(2):512-7. doi:10.1073/pnas.1413291112
Neafsey DE, Waterhouse RM, Abai MR, et al. Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes. Science. 2015;347(6217):1258522. doi:10.1126/science.1258522