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Autonomous multistep organic synthesis in a single isothermal solution mediated by a DNA walker.

He Y, Liu DR. Autonomous multistep organic synthesis in a single isothermal solution mediated by a DNA walker. Nat Nanotechnol. 2010;5(11):778-82. doi:10.1038/nnano.2010.190

A general strategy for the evolution of bond-forming enzymes using yeast display.

Chen I, Dorr BM, Liu DR. A general strategy for the evolution of bond-forming enzymes using yeast display. Proc Natl Acad Sci U S A. 2011;108(28):11399-404. doi:10.1073/pnas.1101046108

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection.

Pattanayak V, Ramirez CL, Joung K, Liu DR. Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection. Nat Methods. 2011;8(9):765-70. doi:10.1038/nmeth.1670

A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes.

Leconte AM, Dickinson BC, Yang DD, Chen IA, Allen B, Liu DR. A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes. Biochemistry. 2013;52(8):1490-9. doi:10.1021/bi3016185

Discovery of widespread GTP-binding motifs in genomic DNA and RNA.

Curtis EA, Liu DR. Discovery of widespread GTP-binding motifs in genomic DNA and RNA. Chem Biol. 2013;20(4):521-32. doi:10.1016/j.chembiol.2013.02.015

High-resolution haplotype structure in the human genome.

Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES. High-resolution haplotype structure in the human genome. Nat Genet. 2001;29(2):229-32. doi:10.1038/ng1001-229

A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant.

Sidow A, Bulotsky MS, Kerrebrock AW, et al. A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nat Genet. 1999;23(1):104-7. doi:10.1038/12709

ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF.

Engert JC, Bérubé P, Mercier J, et al. ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF. Nat Genet. 2000;24(2):120-5. doi:10.1038/72769

CLN5, a novel gene encoding a putative transmembrane protein mutated in Finnish variant late infantile neuronal ceroid lipofuscinosis.

Savukoski M, Klockars T, Holmberg V, Santavuori P, Lander ES, Peltonen L. CLN5, a novel gene encoding a putative transmembrane protein mutated in Finnish variant late infantile neuronal ceroid lipofuscinosis. Nat Genet. 1998;19(3):286-8. doi:10.1038/975

Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes.

Wiseman RW, Cochran C, Dietrich W, Lander ES, Söderkvist P. Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes. Proc Natl Acad Sci U S A. 1994;91(9):3759-63.