Photo of Seth Sharp, ӳý institute

Contact information

Contact Seth Sharp via email at ssharp@broadinstitute.org.

Seth Sharp, Ph.D.

Photo of Seth Sharp, ӳý institute

Seth A. Sharp is a computational biologist and research scientist II in the Udler Lab within the Diabetes Genetics Research Group at the ӳý of MIT and Harvard. He leverages multimodal data to develop translational approaches for precision medicine in diabetes and metabolic disease, including and therapeutic target identification. His expertise spans bioinformatics through to clinical translation, including multi-omics, machine learning, and perturbation data.

Sharp developed the type 1 diabetes , now widely used for screening in global prevention trials, and co-developed an assay for combined newborn screening with celiac disease from dried blood spots. He is a member of the expert working group for type 1 diabetes screening.

He completed his postdoctoral training at Stanford University where he led a genome-wide association study of insulin secretion from human donor islets. He received his Ph.D. from the University of Exeter in the United Kingdom, where he was seconded to the Alan Turing Institute in London.

June 2025