Ó³»´«Ã½ cancer research includes efforts to decipher the genetic and molecular landscape of a wide range of cancer and immune cells as well as equally systematic genome-wide approaches to interrogate the function of cancer genes and the vulnerabilities of tumors. In partnership with colleagues within academia and industry, Ó³»´«Ã½ cancer researchers develop breakthrough technologies to drive discoveries of new drug targets and potential therapies, and generate systematic strategies for predicting therapeutic combinations to combat resistance.
Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses a genome-wide shRNA library to silence individual genes and identify those genes that affect cell survival. Large-scale functional screening of cancer cell lines...
Home of documentation, dashboards and pipeline results for TCGA data & analysis
The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE)...
The Tumorscape portal facilitates the use and understanding of high resolution copy number data amassed from multiple cancer types. It supports gene-level analysis, analysis by cancer type, and the downloading/browsing of data.