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A clinical study comparing liquid and tissue biopsies finds multiple resistance mechanisms in individual patients, which could explain why targeted therapies often fail.

Analysis of single glioblastoma cells shows that they can flip between four different states

Analyzing RNA sequencing data pinpoints ‘somatic clones,’ including some harboring cancer mutations, in many types of normal tissue.

By matching cells' growth trajectories to their genetic features, a team finds CLL cells' arc of growth is written into their genes early in disease development.

By probing the molecular basis of proteasome inhibitor resistance in cancer cells, a Ó³»­´«Ã½-led team finds new vulnerability — and compounds that exploit it.

Researchers take a broad, multi-faceted look at a large collection of cancer cell lines, creating a new trove of data to explore for drug development opportunities.

Calculating genetic risk scores for obesity, new insights about leukemia drugs, and more.