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Researchers used Perturb-CITE-seq to identify a protein involved in resistance to immune checkpoint inhibitors.

Two cancer geneticists make the case for moving beyond tumor sequencing studies.

Study of T cells from glioma tumors identifies a pathway that inhibits immune response

New computational tool uses gene expression data to measure how closely laboratory cancer models compare to real tumors

Genetic screens point to VPS4A and VPS4B as promising cancer drug targets

The Metastasis Map can help researchers learn what causes some tumors to disseminate to different organs.

Study probes interplay of genetics, ancestry, and environment in cancer risk

Combined approach defines new subtypes of breast cancer, yields insights into targetable pathways and that could help match tumors to therapy.

Two teams show how inherited mutations can increase a person’s risk of accumulating sporadic mutations in their blood stem cells.

Ó³»­´«Ã½ scientists are using brain, kidney, and tumor organoids to gain new insights into disease mechanisms and therapeutic approaches.