The molecules mimic a gene variant that protects against Crohn’s, demonstrating a roadmap for using genetics to develop therapies for inflammatory bowel disease and other chronic inflammatory disorders.
Analysis of more than 314,000 cells from rheumatoid arthritis tissue defines six types of inflammation involving diverse cell types and disease pathways
New method finds compounds that bind and inhibit individual members of a family of key regulatory proteins, called cyclophilins, that have been difficult to target selectively.
Hundreds of thousands of colon cells offer new clues into what goes wrong in an inflammatory bowel disease and why some patients don’t respond to drugs