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The DSP develops software products and operates services that are widely used across the biomedical ecosystem, and plays a pivotal role in several national and international scientific initiatives.

Flagship DSP products and services

• The : A suite of interfaces for managing interactions between data access committees and researchers seeking to access sensitive genomic datasets.
• : The leading open-source variant discovery package for analysis of high-throughput sequencing data.
• : Joint calling and variant filtering scaling to more than 500k genomes and counting.
• : Leveraging the All of Us + AnVIL reference panel to impute genomic data.
• ML4H: Accelerating the real-world use and impact of artificial intelligence across all areas of medicine.
• : A popular set of open-source command-line tools for processing high-throughput sequencing data.
• The : Visualize, explore, and publish interactive single and multiomic single cell data.
• : An open cloud-based platform for accessing data, performing analyses and collaborating securely in the cloud, developed in collaboration with .
• : Visualize how basic scientific research publications translate into clinical impact.

Flagship scientific projects

• : A National Institutes of Health (NIH)-funded initiative that will recruit 1 million or more U.S. citizens and collect their genomic and clinical data. Ó³»­´«Ã½, in collaboration with Vanderbilt and Verily, has built a Workbench-based platform to store, share, and analyze all data generated as part of the program.
• : NHGRI's Genomic Data Science Analysis, Visualization, and Informatics Lab-Space enables biomedical researchers to access data, run analysis tools, and collaborate at scale. AnVIL is built on many DSP technologies, including Trusted Research environments (Terra) and DUOS.
• : An NIH BRAIN Initiative consortium that builds reference brain cell atlases to be widely used throughout the research community, providing a molecular and anatomical foundational framework for the study of brain function and disorders. In partnership with NeMO, DSP builds workflows to uniformly process BICAN atlas data.
• : A cloud-based ecosystem offering researchers data, analytic tools, applications, and workflows in secure workspaces.
• : The Data Science for Health Discovery and Innovation in Africa (DS-I Africa) Initiative aims to leverage data science technologies to transform biomedical and public health research and develop solutions that would lead to improved health for individuals and populations.
• The : A global effort to comprehensively characterize a human reference of cell types and cell states. Ó³»­´«Ã½ DSP developed and operates parts of the HCA Data Portal, specifically focusing on ingest, storage, and access for managed and unmanaged multimodal sequencing data.
• : Builds an open-access reference resource of a comprehensive, dynamic, 3-D molecular atlas of the late-stage developing human lung with data and reagents available to the research community.
• : A cloud-based research platform for population health research focused on better data for and use of AI, providing training opportunities for data science, and cloud computing resources.
• : A data coordination, analysis, and scientific outreach center established to standardize and share single-cell molecular data to inform pathophysiological understanding of CNS effects of substance use disorders and HIV.