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This week, Nature Genetics included papers on two new methods for leveraging large cohort studies. One paper — from the Ó³»­´«Ã½â€™s Program in (MPG) and , along with a team of collaborators — shares a powerful in genome-wide association studies (GWAS). The other — also with contributions from MPG — that vastly increases computation speed while simultaneously increasing the statistical power of large data sets.