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In his September 13, TEDxCambridge lecture, ‘Decoding a Genomic Revolution,’ ӳý associate member and MIT associate professor Manolis Kellis used details from his own genome to demonstrate how science can bridge the gap between genetic variants and disease.

Check out the video below and accompany Kellis on a journey into his personal genome to find out how recent discoveries could change the future of medical care.

There is no final chapter in the Cancer Cell Line Encyclopedia. Like many resources and tools in biomedicine, researchers are rewriting and expanding this metaphorical book. The encyclopedia has grown well beyond genomes and now contains many different pieces of information on 1,000 cell lines representing more than 20 different kinds of cancer.

Cancer has come to be known as a “disease of the genome.” Any number of alterations to an individual’s genetic code – the sequence of As, Cs, Gs, and Ts that serve as our biological blueprint – has the potential to make a cell malfunction and proliferate into cancer tumors. Identifying the genetic changes that lead to cancer – and the rules that govern those changes – has been a key goal in the field of cancer genomics. It is a task made more challenging by the diversity of cancer types and the seemingly distinct biology of different types of cancers.