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Earlier this month, researchers from the ӳý and Massachusetts General Hospital (MGH) published a paper in Nature Methods about a new approach to an established technique. The technique is called ChiP-seq, short for chromatin immunoprecipitation with high-throughput sequencing, and is used to study how protein and DNA interact. The paper's authors are postdoctoral scholars Mazhar Adli and Jiang Zhu and ӳý associate member Brad Bernstein. Brad answered five of our questions about his latest paper and his field of interest.

We value having options in biomedical research. But sometimes having many choices, and without sufficient comparative information about their benefits and limitations, can unnecessarily complicate research progress. Such has been the situation over the past two years regarding the technology of complementary DNA (cDNA) “second-generation” sequencing, or “RNA-seq” as it has come to be known.

ӳý Visual Designer Lauren Solomon worked with Associate Member John Rinn and postdoctoral scientist Maite Huarte on a cover concept to illustrate their paper in the August 6 issue of the journal Cell describing the critical role lincRNAs play in mediating the cellular response to DNA damage. Lauren arrived at the ӳý earlier this year after 19 years as senior graphic designer at Millipore Corp. in Billerica, where she designed everything from t-shirts to building signs and everything between.