Krishnan A. A generative deep learning approach to de novo antibiotic design. Cell. 2025. doi:10.1016/j.cell.2025.07.033
Infectious Disease and Microbiome Program, Infectious Disease and Microbiome
Liu Y, Gu X, Li Y, et al. Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function. Nature medicine. 2025. doi:10.1038/s41591-025-03891-5
Park JD, Lee SR, Dhennezel C, et al. Elucidating the role of Campylobacter concisus-derived indole metabolites in gut inflammation and immune modulation. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(34):e2514071122. doi:10.1073/pnas.2514071122
Kreitz J, Yang V, Friedrich MJ, Pham J, Macrae RK, Zhang F. Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes. Nature biotechnology. 2025. doi:10.1038/s41587-025-02774-x
LaVerriere E, Johnson ZM, Shieh M, et al. Marked heterogeneity in malaria infection rate in a Malian longitudinal cohort. Nature communications. 2025;16(1):6512. doi:10.1038/s41467-025-61462-1
Cartagena AJ, Taylor KL, Smith JT, et al. The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.05.23.541813
Rothhammer V, Mascanfroni ID, Bunse L, et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nat Med. 2016;22(6):586-97. doi:10.1038/nm.4106
Lamas B, Richard ML, Leducq V, et al. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nat Med. 2016;22(6):598-605. doi:10.1038/nm.4102
David LA, Materna AC, Friedman J, et al. Erratum to: Host lifestyle affects human microbiota on daily timescales. Genome Biol. 2016;17(1):117. doi:10.1186/s13059-016-0988-y
Rooks MG, Garrett WS. Gut microbiota, metabolites and host immunity. Nat Rev Immunol. 2016;16(6):341-52. doi:10.1038/nri.2016.42