Kulesa A, Kehe J, Hurtado JE, Tawde P, Blainey PC. Combinatorial drug discovery in nanoliter droplets. Proc Natl Acad Sci U S A. 2018;115(26):6685-6690. doi:10.1073/pnas.1802233115
Rohde JM, Brimacombe KR, Liu L, et al. Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors. Bioorg Med Chem. 2018;26(8):1727-1739. doi:10.1016/j.bmc.2018.02.016
Ross LS, Lafuente-Monasterio MJ, Sakata-Kato T, et al. Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum. ACS Infect Dis. 2018;4(4):508-515. doi:10.1021/acsinfecdis.7b00217
Niepel M, Hafner M, Duan Q, et al. Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling. Nat Commun. 2017;8(1):1186. doi:10.1038/s41467-017-01383-w
Shapiro RS, Chavez A, Porter CBM, et al. A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans. Nat Microbiol. 2018;3(1):73-82. doi:10.1038/s41564-017-0043-0
Maji B, Gangopadhyay SA, Lee M, et al. A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9. Cell. 2019;177(4):1067-1079.e19. doi:10.1016/j.cell.2019.04.009
Chiang WC, Wei Y, Kuo YC, et al. High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding. ACS Chem Biol. 2018;13(8):2247-2260. doi:10.1021/acschembio.8b00421
Radke JB, Carey KL, Shaw S, et al. High Throughput Screen Identifies Interferon γ-Dependent Inhibitors of Toxoplasma gondii Growth. ACS Infect Dis. 2018;4(10):1499-1507. doi:10.1021/acsinfecdis.8b00135
Donlin LT, Rao DA, Wei K, et al. Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue. Arthritis Res Ther. 2018;20(1):139. doi:10.1186/s13075-018-1631-y
Simm J, Klambauer G, Arany A, et al. Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery. Cell Chem Biol. 2018;25(5):611-618.e3. doi:10.1016/j.chembiol.2018.01.015