Nühs A, De Rycker M, Manthri S, et al. Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity. PLoS Negl Trop Dis. 2015;9(9):e0004094. doi:10.1371/journal.pntd.0004094
Kuo SY, Castoreno AB, Aldrich LN, et al. Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics. Proc Natl Acad Sci U S A. 2015;112(31):E4281-7. doi:10.1073/pnas.1512289112
Arrowsmith CH, Audia JE, Austin C, et al. The promise and peril of chemical probes. Nat Chem Biol. 2015;11(8):536-41. doi:10.1038/nchembio.1867
Chen J, Peterson RT, Schreiber SL. Alpha 4 associates with protein phosphatases 2A, 4, and 6. Biochem Biophys Res Commun. 1998;247(3):827-32. doi:10.1006/bbrc.1998.8792
Lukens AK, Heidebrecht RW, Mulrooney C, et al. Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors. J Infect Dis. 2015;211(7):1097-103. doi:10.1093/infdis/jiu565
Aldrich LN, Kuo SY, Castoreno AB, et al. Discovery of a Small-Molecule Probe for V-ATPase Function. J Am Chem Soc. 2015;137(16):5563-8. doi:10.1021/jacs.5b02150
Iaconelli J, Huang JH, Berkovitch SS, et al. HDAC6 inhibitors modulate Lys49 acetylation and membrane localization of β-catenin in human iPSC-derived neuronal cells. ACS Chem Biol. 2015;10(3):883-90. doi:10.1021/cb500838r
Sundberg TB, Choi HG, Song JH, et al. Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells. Proc Natl Acad Sci U S A. 2014;111(34):12468-73. doi:10.1073/pnas.1412308111
Wurst JM, Drake EJ, Theriault JR, et al. Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol. 2014;9(7):1536-44. doi:10.1021/cb5001586
Hassig CA, Tong JK, Schreiber SL. Fiber-derived butyrate and the prevention of colon cancer. Chem Biol. 1997;4(11):783-9.