Iaconelli J, Lalonde J, Watmuff B, et al. Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells. ACS Chem Biol. 2017;12(8):2139-2148. doi:10.1021/acschembio.6b01014
Verderosa AD, de la Fuente-Núñez C, Mansour SC, et al. Ciprofloxacin-nitroxide hybrids with potential for biofilm control. Eur J Med Chem. 2017;138:590-601. doi:10.1016/j.ejmech.2017.06.058
Chan AI, McGregor LM, Jain T, Liu DR. Discovery of a Covalent Kinase Inhibitor from a DNA-Encoded Small-Molecule Library × Protein Library Selection. J Am Chem Soc. 2017;139(30):10192-10195. doi:10.1021/jacs.7b04880
Verho O, Maetani M, Melillo B, Zoller J, Schreiber SL. Stereospecific Palladium-Catalyzed C-H Arylation of Pyroglutamic Acid Derivatives at the C3 Position Enabled by 8-Aminoquinoline as a Directing Group. Org Lett. 2017;19(17):4424-4427. doi:10.1021/acs.orglett.7b01776
Reczek CR, Birsoy K, Kong H, et al. A CRISPR screen identifies a pathway required for paraquat-induced cell death. Nat Chem Biol. 2017;13(12):1274-1279. doi:10.1038/nchembio.2499
LaRochelle JR, Fodor M, Ellegast JM, et al. Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2. Bioorg Med Chem. 2017;25(24):6479-6485. doi:10.1016/j.bmc.2017.10.025
Casini A, Chang FY, Eluere R, et al. A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology. J Am Chem Soc. 2018;140(12):4302-4316. doi:10.1021/jacs.7b13292
Rohde JM, Brimacombe KR, Liu L, et al. Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors. Bioorg Med Chem. 2018;26(8):1727-1739. doi:10.1016/j.bmc.2018.02.016
Hajian B, Scocchera E, Shoen C, et al. Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents. Cell Chem Biol. 2019;26(6):781-791.e6. doi:10.1016/j.chembiol.2019.02.013
Kelly AR, Wei J, Kesavan S, et al. Accessing skeletal diversity using catalyst control: formation of n and n + 1 macrocyclic triazole rings. Org Lett. 2009;11(11):2257-60. doi:10.1021/ol900562u