Altshuler D, Hirschhorn JN, Klannemark M, et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet. 2000;26(1):76-80. doi:10.1038/79216
Cowles CR, Hirschhorn JN, Altshuler D, Lander ES. Detection of regulatory variation in mouse genes. Nat Genet. 2002;32(3):432-7. doi:10.1038/ng992
Lander ES, Botstein D. Strategies for studying heterogeneous genetic traits in humans by using a linkage map of restriction fragment length polymorphisms. Proc Natl Acad Sci U S A. 1986;83(19):7353-7.
Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466(7307):707-13. doi:10.1038/nature09270
Castro VM, Minnier J, Murphy SN, et al. Validation of electronic health record phenotyping of bipolar disorder cases and controls. Am J Psychiatry. 2015;172(4):363-72. doi:10.1176/appi.ajp.2014.14030423
Usher CL, McCarroll SA. Complex and multi-allelic copy number variation in human disease. Brief Funct Genomics. 2015;14(5):329-38. doi:10.1093/bfgp/elv028
Hill K, Buchholz A, Amsbaugh H, et al. Working memory impairment in probands with schizoaffective disorder and first degree relatives of schizophrenia probands extend beyond deficits predicted by generalized neuropsychological impairment. Schizophr Res. 2015;166(1-3):310-5. doi:10.1016/j.schres.2015.05.018
Brenan L, Andreev A, Cohen O, et al. Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants. Cell Rep. 2016;17(4):1171-1183. doi:10.1016/j.celrep.2016.09.061
Wagner BK, Schreiber SL. The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods. Cell Chem Biol. 2016;23(1):3-9. doi:10.1016/j.chembiol.2015.11.008
Wagner BK. The resurgence of phenotypic screening in drug discovery and development. Expert Opin Drug Discov. 2016;11(2):121-5. doi:10.1517/17460441.2016.1122589