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Using Droplet Digital PCR to Analyze Allele-Specific RNA Expression.

Kamitaki N, Usher CL, McCarroll SA. Using Droplet Digital PCR to Analyze Allele-Specific RNA Expression. Methods Mol Biol. 2018;1768:401-422. doi:10.1007/978-1-4939-7778-9_23

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood.

Ni G, Moser G, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray NR, Lee H. Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood. Am J Hum Genet. 2018;102(6):1185-1194. doi:10.1016/j.ajhg.2018.03.021

The critical needs and challenges for genetic architecture studies in Africa.

Martin AR, Teferra S, Möller M, Hoal EG, Daly MJ. The critical needs and challenges for genetic architecture studies in Africa. Curr Opin Genet Dev. 2018;53:113-120. doi:10.1016/j.gde.2018.08.005

Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018).

Lam M, Trampush JW, Yu J, et al. Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018). Twin Res Hum Genet. 2018;21(5):394-397. doi:10.1017/thg.2018.46

Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits.

Hormozdiari F, Gazal S, van de Geijn B, et al. Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits. Nat Genet. 2018;50(7):1041-1047. doi:10.1038/s41588-018-0148-2

Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations.

Gazal S, Loh PR, Finucane HK, et al. Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations. Nat Genet. 2018;50(11):1600-1607. doi:10.1038/s41588-018-0231-8

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.

Evans LM, Tahmasbi R, Vrieze SI, et al. Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits. Nat Genet. 2018;50(5):737-745. doi:10.1038/s41588-018-0108-x

Phenome-wide association studies across large population cohorts support drug target validation.

Diogo D, Tian C, Franklin CS, et al. Phenome-wide association studies across large population cohorts support drug target validation. Nat Commun. 2018;9(1):4285. doi:10.1038/s41467-018-06540-3

Using ALoFT to determine the impact of putative loss-of-function variants in protein-coding genes.

Balasubramanian S, Fu Y, Pawashe M, et al. Using ALoFT to determine the impact of putative loss-of-function variants in protein-coding genes. Nat Commun. 2017;8(1):382. doi:10.1038/s41467-017-00443-5

Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.

Zhang G, Feenstra B, Bacelis J, et al. Genetic Associations with Gestational Duration and Spontaneous Preterm Birth. N Engl J Med. 2017;377(12):1156-1167. doi:10.1056/NEJMoa1612665