Wagner BK, Clemons PA. Connecting synthetic chemistry decisions to cell and genome biology using small-molecule phenotypic profiling. Curr Opin Chem Biol. 2009;13(5-6):539-48. doi:10.1016/j.cbpa.2009.09.018
Tanikawa T, Fridman M, Zhu W, et al. Using biological performance similarity to inform disaccharide library design. J Am Chem Soc. 2009;131(14):5075-83. doi:10.1021/ja806583y
Chan AI, McGregor LM, Liu DR. Novel selection methods for DNA-encoded chemical libraries. Curr Opin Chem Biol. 2015;26:55-61. doi:10.1016/j.cbpa.2015.02.010
Kleiner RE, Dumelin CE, Liu DR. Small-molecule discovery from DNA-encoded chemical libraries. Chem Soc Rev. 2011;40(12):5707-17. doi:10.1039/c1cs15076f
He Y, Liu DR. A sequential strand-displacement strategy enables efficient six-step DNA-templated synthesis. J Am Chem Soc. 2011;133(26):9972-5. doi:10.1021/ja201361t
McGregor LM, Gorin DJ, Dumelin CE, Liu DR. Interaction-dependent PCR: identification of ligand-target pairs from libraries of ligands and libraries of targets in a single solution-phase experiment. J Am Chem Soc. 2010;132(44):15522-4. doi:10.1021/ja107677q
Kleiner RE, Dumelin CE, Tiu GC, Sakurai K, Liu DR. In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors. J Am Chem Soc. 2010;132(33):11779-91. doi:10.1021/ja104903x
Ichida JK, Blanchard J, Lam K, et al. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell. 2009;5(5):491-503. doi:10.1016/j.stem.2009.09.012
Schreiber SL, Kotz JD, Li M, et al. Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes. Cell. 2015;161(6):1252-65. doi:10.1016/j.cell.2015.05.023
Schaefer GI, Perez JR, Duvall JR, Stanton BZ, Shamji AF, Schreiber SL. Discovery of small-molecule modulators of the Sonic Hedgehog pathway. J Am Chem Soc. 2013;135(26):9675-80. doi:10.1021/ja400034k