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Laboratory study suggests that thalidomide-like drugs could be designed to target a broad array of transcription factors, and open a new landscape of cancer drug development.

Study may help predict patient response, reduce treatment resistance

Researchers identify a molecular strategy that human melanoma cells use to resist immunotherapy, and develop a new approach to combat the resistance in mouse models

For the first time, researchers provide comprehensive information about the organization and assembly of protein complexes linked to both cancer and neurological disorders.

Passing on participation, whether cancer mutation hotspots are really that hot, and pinpointing key autoimmunity variants.

In explaining why mutations in the gene TP53 tend to cluster in “hot spots,” a new study lays the groundwork for ability to identify the function of any mutation in any cancer gene.

Research team shows the power of proteomics to discover new drug targets

Risk scores arise, scrutinizing cells' nutrient sensors, learning about lncRNAs, and more.

Researchers predicted these cancer-specific peptides, dubbed "retained intron" neoantigens, by computationally sifting through melanoma patients' tumor RNA.

Through “polygenic risk scoring,” researchers can identify people at high risk for disease, even if they don’t present other warning signs; method shows potential for use in the clinic