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Biopsies taken before and after treatment reveal new resistance route, as well as an opportunity to resensitize metastatic breast cancers to therapy.

Using a new model dubbed DEMETER2, the ӳ����ý's Cancer Dependency Map team has compiled the largest dataset of genetic dependencies in cancer to date.

Laboratory study suggests that thalidomide-like drugs could be designed to target a broad array of transcription factors, and open a new landscape of cancer drug development.

Study may help predict patient response, reduce treatment resistance

Researchers identify a molecular strategy that human melanoma cells use to resist immunotherapy, and develop a new approach to combat the resistance in mouse models

For the first time, researchers provide comprehensive information about the organization and assembly of protein complexes linked to both cancer and neurological disorders.

Passing on participation, whether cancer mutation hotspots are really that hot, and pinpointing key autoimmunity variants.

In explaining why mutations in the gene TP53 tend to cluster in “hot spots,” a new study lays the groundwork for ability to identify the function of any mutation in any cancer gene.

Research team shows the power of proteomics to discover new drug targets

Risk scores arise, scrutinizing cells' nutrient sensors, learning about lncRNAs, and more.