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The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.

Zhou G, Ferrer M, Chopra R, et al. The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorg Med Chem. 2000;8(9):2219-27.

Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A.

Ke H, Mayrose D, Belshaw PJ, et al. Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A. Structure. 1994;2(1):33-44.

n→π* interactions engender chirality in carbonyl groups.

Choudhary A, Newberry RW, Raines RT. n→π* interactions engender chirality in carbonyl groups. Org Lett. 2014;16(13):3421-3. doi:10.1021/ol5012967

Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics.

Krow GR, Shoulders MD, Edupuganti R, et al. Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics. J Org Chem. 2012;77(12):5331-44. doi:10.1021/jo300700a

An n→π* interaction in aspirin: implications for structure and reactivity.

Choudhary A, Kamer KJ, Raines RT. An n→π* interaction in aspirin: implications for structure and reactivity. J Org Chem. 2011;76(19):7933-7. doi:10.1021/jo201389d

Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines.

Krow GR, Edupuganti R, Gandla D, et al. Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines. J Org Chem. 2011;76(10):3626-34. doi:10.1021/jo200117p

An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.

Marcaurelle LA, Comer E, Dandapani S, et al. An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. J Am Chem Soc. 2010;132(47):16962-76. doi:10.1021/ja105119r

Thermodynamics of the conformational transition of biopolyelectrolytes: the case of specific affinity of counterions.

Paoletti S, Benegas JC, Pantano S, Vetere A. Thermodynamics of the conformational transition of biopolyelectrolytes: the case of specific affinity of counterions. Biopolymers. 1999;50(7):705-19. doi:10.1002/(SICI)1097-0282(199912)50:7<705::AID-BIP4>3.0.CO;2-A

Macrocycloadditions leading to conformationally restricted small molecules.

Looper RE, Pizzirani D, Schreiber SL. Macrocycloadditions leading to conformationally restricted small molecules. Org Lett. 2006;8(10):2063-6. doi:10.1021/ol0604724

Continuous directed evolution of aminoacyl-tRNA synthetases.

Bryson DI, Fan C, Guo LT, Miller C, Söll D, Liu DR. Continuous directed evolution of aminoacyl-tRNA synthetases. Nat Chem Biol. 2017;13(12):1253-1260. doi:10.1038/nchembio.2474