Wilson A, Bender A, Kaya T, Clemons PA. Alpha shapes applied to molecular shape characterization exhibit novel properties compared to established shape descriptors. J Chem Inf Model. 2009;49(10):2231-41. doi:10.1021/ci900190z
Uchida T, Rodriquez M, Schreiber SL. Skeletally diverse small molecules using a build/couple/pair strategy. Org Lett. 2009;11(7):1559-62. doi:10.1021/ol900173t
Geng B, Basarab G, Comita-Prevoir J, et al. Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): pyridodiazepine amines. Bioorg Med Chem Lett. 2009;19(3):930-6. doi:10.1016/j.bmcl.2008.11.113
Basarab GS, Kern GH, McNulty J, et al. Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases. Sci Rep. 2015;5:11827. doi:10.1038/srep11827
Luo M, Lin H, Fischbach MA, Liu DR, Walsh CT, Groves JT. Enzymatic tailoring of enterobactin alters membrane partitioning and iron acquisition. ACS Chem Biol. 2006;1(1):29-32. doi:10.1021/cb0500034
Kleiner RE, Brudno Y, Birnbaum ME, Liu DR. DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydes. J Am Chem Soc. 2008;130(14):4646-59. doi:10.1021/ja0753997
Kleiner RE, Dumelin CE, Tiu GC, Sakurai K, Liu DR. In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors. J Am Chem Soc. 2010;132(33):11779-91. doi:10.1021/ja104903x
Fan JA, He Y, Bao K, et al. DNA-enabled self-assembly of plasmonic nanoclusters. Nano Lett. 2011;11(11):4859-64. doi:10.1021/nl203194m
Nelson SD, Wawer MJ, Schreiber SL. Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives. Org Lett. 2016;18(24):6280-6283. doi:10.1021/acs.orglett.6b03118
Rao SSP, Huntley MH, Durand NC, et al. A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Cell. 2014;159(7):1665-80. doi:10.1016/j.cell.2014.11.021