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Cancer Program
Manakongtreecheep K, Ctortecka C, Correa-Medero LO, et al. Sensitive detection of cancer antigens enabled by user-defined peptide libraries. Nature biotechnology. 2026. doi:10.1038/s41587-026-03003-9
Camp SY, He MX, Cuoco MS, et al. Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and loss. Science advances. 2026;12(8):eadv5457. doi:10.1126/sciadv.adv5457
Law CT, Burns KH. Comparative genomics reveals LINE-1 recombination with diverse RNAs. Cell genomics. 2026:101165. doi:10.1016/j.xgen.2026.101165
Levesque S, Bauer DE. CRISPR-based therapeutic genome editing for inherited blood disorders. Nature reviews. Drug discovery. 2025. doi:10.1038/s41573-025-01236-y
Lightbody ED, Sklavenitis-Pistofidis R, Wu T, et al. SWIFT-seq enables comprehensive single-cell transcriptomic profiling of circulating tumor cells in multiple myeloma and its precursors. Nature cancer. 2025. doi:10.1038/s43018-025-01006-0
Guo JA, Gong D, Evans K, et al. Integrative genomic identification of therapeutic targets for pancreatic cancer. Cell reports. 2025;44(9):116191. doi:10.1016/j.celrep.2025.116191
Parsons HA, Messer C, Santos K, et al. Detection of heterogeneous resistance mechanisms to tyrosine kinase inhibitors from cell-free DNA. Cell genomics. 2025:100987. doi:10.1016/j.xgen.2025.100987
Knudsen NH, Escobar G, Korell F, et al. In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma. Nature. 2025. doi:10.1038/s41586-025-09489-8
Yang J, Wang C, Fu D, et al. Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma. Nature communications. 2025;16(1):8151. doi:10.1038/s41467-025-62878-5