Gillani R, Seong BKA, Crowdis J, et al. Gene fusions create partner and collateral dependencies essential to cancer cell survival. Cancer Res. 2021. doi:10.1158/0008-5472.CAN-21-0791
Cancer Program
Wu Z, Zhou J, Zhang X, et al. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nat Genet. 2021;53(6):881-894. doi:10.1038/s41588-021-00859-2
Henley MJ, Koehler AN. Advances in targeting ’undruggable’ transcription factors with small molecules. Nat Rev Drug Discov. 2021. doi:10.1038/s41573-021-00199-0
Shareef SJ, Bevill SM, Raman AT, et al. Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells. Nat Biotechnol. 2021. doi:10.1038/s41587-021-00910-x
Griffin GK, Wu J, Iracheta-Vellve A, et al. Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity. Nature. 2021. doi:10.1038/s41586-021-03520-4
Boehm JS. The power of parent scientists. Cell. 2021;184(9):2263-2270. doi:10.1016/j.cell.2021.03.049
Way GP, Kost-Alimova M, Shibue T, et al. Predicting cell health phenotypes using image-based morphology profiling. Mol Biol Cell. 2021;32(9):995-1005. doi:10.1091/mbc.E20-12-0784
Cieri N, Wu CJ. Splice it up: Atypical transcripts to boost leukemia immunotherapy. Immunity. 2021;54(4):608-610. doi:10.1016/j.immuni.2021.03.016
Dharia NV, Kugener G, Guenther LM, et al. A first-generation pediatric cancer dependency map. Nat Genet. 2021;53(4):529-538. doi:10.1038/s41588-021-00819-w
Noorbakhsh J, Vazquez F, McFarland JM. Bridging the gap between cancer cell line models and tumours using gene expression data. Br J Cancer. 2021. doi:10.1038/s41416-021-01359-0