Carrasquillo MM, Allen M, Burgess JD, et al. A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer’s disease risk and increased TREML1 and TREM2 brain gene expression. Alzheimers Dement. 2016. doi:10.1016/j.jalz.2016.10.005
Medical and Population Genetics Program
Yu L, Chibnik LB, Yang J, et al. Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer’s disease pathology. Alzheimers Dement. 2016;12(9):942-51. doi:10.1016/j.jalz.2016.02.009
Fuchsberger C, Flannick J, Teslovich TM, et al. The genetic architecture of type 2 diabetes. Nature. 2016;536(7614):41-7. doi:10.1038/nature18642
Boettger LM, Salem RM, Handsaker RE, et al. Recurring exon deletions in the HP (haptoglobin) gene contribute to lower blood cholesterol levels. Nat Genet. 2016;48(4):359-66. doi:10.1038/ng.3510
Hohman TJ, Cooke-Bailey JN, Reitz C, et al. Global and local ancestry in African-Americans: Implications for Alzheimer’s disease risk. Alzheimers Dement. 2016;12(3):233-43. doi:10.1016/j.jalz.2015.02.012
Loh PR, Tucker G, Bulik-Sullivan BK, et al. Efficient Bayesian mixed-model analysis increases association power in large cohorts. Nat Genet. 2015;47(3):284-90. doi:10.1038/ng.3190
Bulik-Sullivan BK, Loh PR, Finucane HK, et al. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet. 2015;47(3):291-5. doi:10.1038/ng.3211
Do R, Balick D, Li H, Adzhubei I, Sunyaev S, Reich D. No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans. Nat Genet. 2015;47(2):126-31. doi:10.1038/ng.3186
Convergent genetic and expression data implicate immunity in Alzheimer’s disease. Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2015;11(6):658-71. doi:10.1016/j.jalz.2014.05.1757
PMCID
PMC4672734
Sherva R, Tripodis Y, Bennett DA, et al. Genome-wide association study of the rate of cognitive decline in Alzheimer’s disease. Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2014;10(1):45-52. doi:10.1016/j.jalz.2013.01.008
PMCID
PMC3760995