Publications

Stanley Center for Psychiatric Research

Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex.

Uzquiano A, Kedaigle AJ, Pigoni M, et al. Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex. Cell. 2022;185(20):3770-3788.e27. doi:10.1016/j.cell.2022.09.010

Optogenetic polymerization and assembly of electrically functional polymers for modulation of single-neuron excitability.

Sessler C, Zhou Y, Wang W, et al. Optogenetic polymerization and assembly of electrically functional polymers for modulation of single-neuron excitability. Science advances. 2022;8(49):eade1136. doi:10.1126/sciadv.ade1136

Predicting functional effects of missense variants in voltage-gated sodium and calcium channels.

Heyne HO, Baez-Nieto D, Iqbal S, et al. Predicting functional effects of missense variants in voltage-gated sodium and calcium channels. Sci Transl Med. 2020;12(556). doi:10.1126/scitranslmed.aay6848

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Bis JC, Jian X, Kunkle BW, et al. Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry. 2020;25(8):1859-1875. doi:10.1038/s41380-018-0112-7

Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome.

McCamphill PK, Stoppel LJ, Senter RK, et al. Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome. Sci Transl Med. 2020;12(544). doi:10.1126/scitranslmed.aam8572

Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits.

Ghoshal A, Uygun DS, Yang L, et al. Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits. Transl Psychiatry. 2020;10(1):29. doi:10.1038/s41398-020-0685-1

Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes.

Guo SM, Veneziano R, Gordonov S, et al. Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes. Nat Commun. 2019;10(1):4377. doi:10.1038/s41467-019-12372-6

Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution.

Rodriques SG, Stickels RR, Goeva A, et al. Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution. Science. 2019;363(6434):1463-1467. doi:10.1126/science.aaw1219

Lateral orbitofrontal dysfunction in the Sapap3 knockout mouse model of obsessive–compulsive disorder

Lei H, Lai J, Sun X, Xu Q, Feng G. Lateral orbitofrontal dysfunction in the Sapap3 knockout mouse model of obsessive–compulsive disorder. J Psychiatry Neurosci. 2019;44(2):120-131. doi:10.1503/jpn.180032

Neuropsychiatric Genetics of African Populations-Psychosis (NeuroGAP-Psychosis): a case-control study protocol and GWAS in Ethiopia, Kenya, South Africa and Uganda.

Stevenson A, Akena D, Stroud RE, et al. Neuropsychiatric Genetics of African Populations-Psychosis (NeuroGAP-Psychosis): a case-control study protocol and GWAS in Ethiopia, Kenya, South Africa and Uganda. BMJ Open. 2019;9(2):e025469. doi:10.1136/bmjopen-2018-025469

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Stanley Center for Psychiatric Research

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