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Publications

Gut microbiota utilize immunoglobulin A for mucosal colonization.

Donaldson GP, Ladinsky MS, Yu KB, et al. Gut microbiota utilize immunoglobulin A for mucosal colonization. Science. 2018;360(6390):795-800. doi:10.1126/science.aaq0926

The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress.

Zelikowsky M, Hui M, Karigo T, et al. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell. 2018;173(5):1265-1279.e19. doi:10.1016/j.cell.2018.03.037

Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.

Simm J, Klambauer G, Arany A, et al. Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery. Cell Chem Biol. 2018;25(5):611-618.e3. doi:10.1016/j.chembiol.2018.01.015

A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica.

Estrada K, Whelan CW, Zhao F, et al. A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica. Nat Commun. 2018;9(1):1929. doi:10.1038/s41467-018-04332-3

Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms.

Lin YF, Chen CY, Öngür D, et al. Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms. Transl Psychiatry. 2018;8(1):97. doi:10.1038/s41398-018-0144-4

A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish.

Haesemeyer M, Robson DN, Li JM, Schier AF, Engert F. A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish. Neuron. 2018;98(4):817-831.e6. doi:10.1016/j.neuron.2018.04.013

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families.

Gormley P, Kurki MI, Hiekkala ME, et al. Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families. Neuron. 2018;98(4):743-753.e4. doi:10.1016/j.neuron.2018.04.014

The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.

Pelka K, Bertheloot D, Reimer E, et al. The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport. Immunity. 2018;48(5):911-922.e7. doi:10.1016/j.immuni.2018.04.011

Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins.

Koppel N, Bisanz JE, Pandelia ME, Turnbaugh PJ, Balskus EP. Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins. Elife. 2018;7. doi:10.7554/eLife.33953

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia.

Chen X, Gustafsson S, Whitington T, et al. A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia. Hum Mol Genet. 2018;27(10):1809-1818. doi:10.1093/hmg/ddy094