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Publications

Efficient prime editing in vivo and in vitro using lipid nanoparticles.

Jiang AY, Cristian A, Brooks DL, et al. Efficient prime editing in vivo and in vitro using lipid nanoparticles. Nature nanotechnology. 2026. doi:10.1038/s41565-026-02200-6

Identifying and targeting abnormal mitochondrial localization associated with psychosis.

Haghighi M, McPhie D, Rohban M, et al. Identifying and targeting abnormal mitochondrial localization associated with psychosis. bioRxiv : the preprint server for biology. 2026. doi:10.1101/2025.10.08.676630

PMCID

PMC13232271

Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation.

Nomura M, Raviram R, Schiffman JS, et al. Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation. Nature genetics. 2026. doi:10.1038/s41588-026-02642-7

Deep learning-enabled discovery of antibiotics effective against Neisseria gonorrhoeae.

Anahtar MN, Valeri JA, Modaresi SM, et al. Deep learning-enabled discovery of antibiotics effective against Neisseria gonorrhoeae. Science translational medicine. 2026;18(854):eads4699. doi:10.1126/scitranslmed.ads4699

Evaluating the role of pretraining dataset size and diversity on single-cell foundation model performance.

DenAdel A, Hughes M, Thoutam A, et al. Evaluating the role of pretraining dataset size and diversity on single-cell foundation model performance. Nature methods. 2026. doi:10.1038/s41592-026-03120-y

Cellular Repair and Removal of Protein-Damage Modifications.

Porter AKD, Woo CM. Cellular Repair and Removal of Protein-Damage Modifications. Annual review of biochemistry. 2026;95(1):455-481. doi:10.1146/annurev-biochem-051024-045733

Stabilizing and strengthening the US physician-scientist faculty workforce in academic medicine: a proposed institutional framework.

Williams CS, Allen M, Cooper-Byas P, et al. Stabilizing and strengthening the US physician-scientist faculty workforce in academic medicine: a proposed institutional framework. JCI insight. 2026;11(12). doi:10.1172/jci.insight.205939

Genomic, Clinical, and Spatial Predictors of Durable Response to BRAF/MEK Inhibition in -Mutant Melanoma.

Shi Y, Savchenko A, Brase JC, et al. Genomic, Clinical, and Spatial Predictors of Durable Response to BRAF/MEK Inhibition in -Mutant Melanoma. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.05.09.721157

PMCID

PMC13192995

Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders.

Jin Y, Guo Y, Koller JM, et al. Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.05.16.26353368

PMCID

PMC13228652

A community machine learning challenge to predict the effects of gene perturbations on T cell differentiation for cancer immunotherapy.

Zhang J, Schwartz MA, Mutaher M, et al. A community machine learning challenge to predict the effects of gene perturbations on T cell differentiation for cancer immunotherapy. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.05.21.726863

PMCID

PMC13228547