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Publications

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

Gusarova V, O’Dushlaine C, Teslovich TM, et al. Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes. Nat Commun. 2018;9(1):2252. doi:10.1038/s41467-018-04611-z

Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses.

Besnard A, Langberg T, Levinson S, et al. Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses. Cell Rep. 2018;23(11):3183-3196. doi:10.1016/j.celrep.2018.05.040

Integrated Molecular Characterization of Testicular Germ Cell Tumors.

Shen H, Shih J, Hollern DP, et al. Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Rep. 2018;23(11):3392-3406. doi:10.1016/j.celrep.2018.05.039

Enhanced Monte Carlo Methods for Modeling Proteins Including Computation of Absolute Free Energies of Binding.

de Vaca IC, Qian Y, Vilseck JZ, Tirado-Rives J, Jorgensen WL. Enhanced Monte Carlo Methods for Modeling Proteins Including Computation of Absolute Free Energies of Binding. J Chem Theory Comput. 2018;14(6):3279-3288. doi:10.1021/acs.jctc.8b00031

ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.

Oveisgharan S, Buchman AS, Yu L, et al. ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults. Neurology. 2018;90(24):e2127-e2134. doi:10.1212/WNL.0000000000005677

Multi-ethnic genome-wide association study for atrial fibrillation.

Roselli C, Chaffin MD, Weng LC, et al. Multi-ethnic genome-wide association study for atrial fibrillation. Nat Genet. 2018;50(9):1225-1233. doi:10.1038/s41588-018-0133-9

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma.

McBride MJ, Pulice JL, Beird HC, et al. The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma. Cancer Cell. 2018;33(6):1128-1141.e7. doi:10.1016/j.ccell.2018.05.002

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood.

Ni G, Moser G, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray NR, Lee H. Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood. Am J Hum Genet. 2018;102(6):1185-1194. doi:10.1016/j.ajhg.2018.03.021

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum.

Ganna A, Satterstrom K, Zekavat SM, et al. Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum. Am J Hum Genet. 2018;102(6):1204-1211. doi:10.1016/j.ajhg.2018.05.002

Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.

Nowak C, Hetty S, Salihovic S, et al. Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance. Sci Rep. 2018;8(1):8691. doi:10.1038/s41598-018-26701-0