Huang K lin, Mashl J, Wu Y, et al. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell. 2018;173(2):355-370.e14. doi:10.1016/j.cell.2018.03.039
Publications
Bailey MH, Tokheim C, Porta-Pardo E, et al. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018;173(2):371-385.e18. doi:10.1016/j.cell.2018.02.060
Liu J, Lichtenberg T, Hoadley KA, et al. An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell. 2018;173(2):400-416.e11. doi:10.1016/j.cell.2018.02.052
Cesana M, Guo MH, Cacchiarelli D, et al. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell. 2018;22(4):575-588.e7. doi:10.1016/j.stem.2018.03.012
Shen K, Huang RK, Brignole EJ, et al. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes. Nature. 2018;556(7699):64-69. doi:10.1038/nature26158
Ziller MJ, Ortega JA, Quinlan KA, et al. Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell. 2018;22(4):559-574.e9. doi:10.1016/j.stem.2018.02.012
Hu JH, Miller SM, Geurts MH, et al. Evolved Cas9 variants with broad PAM compatibility and high DNA specificity. Nature. 2018;556(7699):57-63. doi:10.1038/nature26155
Brown EM, Xavier RJ. Without Adaptive Immunity, There’s a Cost to Responding STAT. Cell Metab. 2018;27(4):705-707. doi:10.1016/j.cmet.2018.03.011
Way GP, Sanchez-Vega F, La K, et al. Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Rep. 2018;23(1):172-180.e3. doi:10.1016/j.celrep.2018.03.046
Campbell JD, Yau C, Bowlby R, et al. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Rep. 2018;23(1):194-212.e6. doi:10.1016/j.celrep.2018.03.063