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Publications

Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.

Ding J, Condon A, Shah SP. Interpretable dimensionality reduction of single cell transcriptome data with deep generative models. Nat Commun. 2018;9(1):2002. doi:10.1038/s41467-018-04368-5

The importance of true collaboration in efforts to increase diversity in genetic analyses.

Hyman SE. The importance of true collaboration in efforts to increase diversity in genetic analyses. Curr Biol. 2018;28(10):R598. doi:10.1016/j.cub.2018.04.039

Understanding Biological Regulation Through Synthetic Biology.

Bashor CJ, Collins JJ. Understanding Biological Regulation Through Synthetic Biology. Annu Rev Biophys. 2018;47:399-423. doi:10.1146/annurev-biophys-070816-033903

NUFIP1 is a ribosome receptor for starvation-induced ribophagy.

Wyant GA, Abu-Remaileh M, Frenkel EM, et al. NUFIP1 is a ribosome receptor for starvation-induced ribophagy. Science. 2018;360(6390):751-758. doi:10.1126/science.aar2663

A Common Mechanism Links Activities of Butyrate in the Colon.

Verma MS, Fink MJ, Salmon GL, et al. A Common Mechanism Links Activities of Butyrate in the Colon. ACS Chem Biol. 2018;13(5):1291-1298. doi:10.1021/acschembio.8b00073

Gut microbiota utilize immunoglobulin A for mucosal colonization.

Donaldson GP, Ladinsky MS, Yu KB, et al. Gut microbiota utilize immunoglobulin A for mucosal colonization. Science. 2018;360(6390):795-800. doi:10.1126/science.aaq0926

The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress.

Zelikowsky M, Hui M, Karigo T, et al. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell. 2018;173(5):1265-1279.e19. doi:10.1016/j.cell.2018.03.037

Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.

Simm J, Klambauer G, Arany A, et al. Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery. Cell Chem Biol. 2018;25(5):611-618.e3. doi:10.1016/j.chembiol.2018.01.015

A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica.

Estrada K, Whelan CW, Zhao F, et al. A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica. Nat Commun. 2018;9(1):1929. doi:10.1038/s41467-018-04332-3

Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms.

Lin YF, Chen CY, Öngür D, et al. Polygenic pleiotropy and potential causal relationships between educational attainment, neurobiological profile, and positive psychotic symptoms. Transl Psychiatry. 2018;8(1):97. doi:10.1038/s41398-018-0144-4