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Publications

is a colitis risk gene that regulates stability of epithelial adherens junctions.

Mohanan V, Nakata T, Desch N, et al. is a colitis risk gene that regulates stability of epithelial adherens junctions. Science. 2018;359(6380):1161-1166. doi:10.1126/science.aan0814

Targeting Antibiotic Tolerance, Pathogen by Pathogen.

Meylan S, Andrews IW, Collins JJ. Targeting Antibiotic Tolerance, Pathogen by Pathogen. Cell. 2018;172(6):1228-1238. doi:10.1016/j.cell.2018.01.037

The genomic history of southeastern Europe.

Mathieson I, Alpaslan-Roodenberg S, Posth C, et al. The genomic history of southeastern Europe. Nature. 2018;555(7695):197-203. doi:10.1038/nature25778

The Beaker phenomenon and the genomic transformation of northwest Europe.

Olalde I, Brace S, Allentoft ME, et al. The Beaker phenomenon and the genomic transformation of northwest Europe. Nature. 2018;555(7695):190-196. doi:10.1038/nature25738

Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma.

Qian ZR, Rubinson DA, Nowak JA, et al. Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma. JAMA Oncol. 2018;4(3):e173420. doi:10.1001/jamaoncol.2017.3420

Improving genetic prediction by leveraging genetic correlations among human diseases and traits.

Maier RM, Zhu Z, Lee SH, et al. Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nat Commun. 2018;9(1):989. doi:10.1038/s41467-017-02769-6

Genome-wide analysis yields new loci associating with aortic valve stenosis.

Helgadottir A, Thorleifsson G, Gretarsdottir S, et al. Genome-wide analysis yields new loci associating with aortic valve stenosis. Nat Commun. 2018;9(1):987. doi:10.1038/s41467-018-03252-6

Extended Duration Nocturnal Hemodialysis and Changes in Plasma Metabolite Profiles.

Kalim S, Wald R, Yan AT, et al. Extended Duration Nocturnal Hemodialysis and Changes in Plasma Metabolite Profiles. Clin J Am Soc Nephrol. 2018;13(3):436-444. doi:10.2215/CJN.08790817

Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia.

Wagner FF, Benajiba L, Campbell AJ, et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018;10(431). doi:10.1126/scitranslmed.aam8460

Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation.

Weng LC, Preis SR, Hulme OL, et al. Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation. Circulation. 2018;137(10):1027-1038. doi:10.1161/CIRCULATIONAHA.117.031431