Publications

The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy.

Landau DA, Sun C, Rosebrock D, et al. The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy. Nat Commun. 2017;8(1):2185. doi:10.1038/s41467-017-02329-y

Defective STIM-mediated store operated Ca entry in hepatocytes leads to metabolic dysfunction in obesity.

Arruda AP, Pers BM, Parlakgul G, et al. Defective STIM-mediated store operated Ca entry in hepatocytes leads to metabolic dysfunction in obesity. Elife. 2017;6. doi:10.7554/eLife.29968

Alterations in oral bacterial communities are associated with risk factors for oral and oropharyngeal cancer.

Börnigen D, Ren B, Pickard R, et al. Alterations in oral bacterial communities are associated with risk factors for oral and oropharyngeal cancer. Sci Rep. 2017;7(1):17686. doi:10.1038/s41598-017-17795-z

Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2.

LaRochelle JR, Fodor M, Ellegast JM, et al. Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2. Bioorg Med Chem. 2017;25(24):6479-6485. doi:10.1016/j.bmc.2017.10.025

Analysis of persistence and antibiotic response in colorectal cancer.

Bullman S, Pedamallu CS, Sicinska E, et al. Analysis of persistence and antibiotic response in colorectal cancer. Science. 2017;358(6369):1443-1448. doi:10.1126/science.aal5240

Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer.

Goldstein JT, Berger AC, Shih J, et al. Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer. Cancer Res. 2017;77(24):6987-6998. doi:10.1158/0008-5472.CAN-17-1701

Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking.

Kaewsapsak P, Shechner DM, Mallard W, Rinn JL, Ting AY. Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking. Elife. 2017;6. doi:10.7554/eLife.29224

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.

Puram SV, Tirosh I, Parikh AS, et al. Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer. Cell. 2017;171(7):1611-1624.e24. doi:10.1016/j.cell.2017.10.044

Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function.

Yang JH, Bhargava P, McCloskey D, Mao N, Palsson BO, Collins JJ. Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. Cell Host Microbe. 2017;22(6):757-765.e3. doi:10.1016/j.chom.2017.10.020

Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.

Martin-Malpartida P, Batet M, Kaczmarska Z, et al. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun. 2017;8(1):2070. doi:10.1038/s41467-017-02054-6

ӳ����ý

Publications

ӳ��ý