D’Gama AM, Woodworth MB, Hossain AA, et al. Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias. Cell Rep. 2017;21(13):3754-3766. doi:10.1016/j.celrep.2017.11.106
Publications
Lessard S, Francioli L, Alföldi J, et al. Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci. Proc Natl Acad Sci U S A. 2017;114(52):E11257-E11266. doi:10.1073/pnas.1714640114
Wills JW, Summers HD, Hondow N, et al. Characterizing Nanoparticles in Biological Matrices: Tipping Points in Agglomeration State and Cellular Delivery In Vitro. ACS Nano. 2017;11(12):11986-12000. doi:10.1021/acsnano.7b03708
Ranaghan MJ, Durney MA, Mesleh MF, et al. The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity. Biochemistry. 2017;56(51):6639-6651. doi:10.1021/acs.biochem.7b00936
Zhu J, Zhou Q, Shang Y, et al. Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep. 2017;21(13):3781-3793. doi:10.1016/j.celrep.2017.11.107
Akondy RS, Fitch M, Edupuganti S, et al. Origin and differentiation of human memory CD8 T cells after vaccination. Nature. 2017;552(7685):362-367. doi:10.1038/nature24633
Gutierrez A, Jain S, Bhargava P, Hamblin M, Lobritz MA, Collins JJ. Understanding and Sensitizing Density-Dependent Persistence to Quinolone Antibiotics. Mol Cell. 2017;68(6):1147-1154.e3. doi:10.1016/j.molcel.2017.11.012
Rabani M, Pieper L, Chew GL, Schier AF. A Massively Parallel Reporter Assay of 3’ UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Mol Cell. 2017;68(6):1083-1094.e5. doi:10.1016/j.molcel.2017.11.014
Nguyen HT, Bryois J, Kim A, et al. Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders. Genome Med. 2017;9(1):114. doi:10.1186/s13073-017-0497-y
Ryan KJ, White CC, Patel K, et al. A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants. Sci Transl Med. 2017;9(421). doi:10.1126/scitranslmed.aai7635