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Publications

Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants.

Lin WY, Chen WJ, Liu CM, et al. Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants. Sci Rep. 2017;7(1):13858. doi:10.1038/s41598-017-13177-7

Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.

Leshchiner ES, Rush JS, Durney MA, et al. Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease. Proc Natl Acad Sci U S A. 2017;114(43):11392-11397. doi:10.1073/pnas.1705748114

Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.

Lencer R, Mills LJ, Alliey-Rodriguez N, et al. Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Transl Psychiatry. 2017;7(10):e1249. doi:10.1038/tp.2017.210

is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls.

Rannikmae K, Sivakumaran V, Millar H, et al. is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls. Neurology. 2017;89(17):1829-1839. doi:10.1212/WNL.0000000000004560

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells.

Semrau S, Goldmann JE, Soumillon M, Mikkelsen TS, Jaenisch R, van Oudenaarden A. Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells. Nat Commun. 2017;8(1):1096. doi:10.1038/s41467-017-01076-4

Aspirin exerts high anti-cancer activity in -mutant colon cancer cells.

Gu M, Nishihara R, Chen Y, et al. Aspirin exerts high anti-cancer activity in -mutant colon cancer cells. Oncotarget. 2017;8(50):87379-87389. doi:10.18632/oncotarget.20972

Evidence of reduced recombination rate in human regulatory domains.

Liu Y, Sarkar A, Kheradpour P, Ernst J, Kellis M. Evidence of reduced recombination rate in human regulatory domains. Genome Biol. 2017;18(1):193. doi:10.1186/s13059-017-1308-x

Ectopic colonization of oral bacteria in the intestine drives T1 cell induction and inflammation.

Atarashi K, Suda W, Luo C, et al. Ectopic colonization of oral bacteria in the intestine drives T1 cell induction and inflammation. Science. 2017;358(6361):359-365. doi:10.1126/science.aan4526

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.

Wyant GA, Abu-Remaileh M, Wolfson RL, et al. mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient. Cell. 2017;171(3):642-654.e12. doi:10.1016/j.cell.2017.09.046

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.

Robertson G, Kim J, Al-Ahmadie H, et al. Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell. 2017;171(3):540-556.e25. doi:10.1016/j.cell.2017.09.007